Concurrent Session 3: Epidermal Structure and Function

Amphitheatre C

Date: Thursday 19 September 2019, 14.40-16.10
Room: Amphitheatre C

Chairs: TBA

Program

14.40-14.50 030 (Poster 235)
PPAR-alpha deficiency drives altered bacterial skin colonization and abnormal eicosanoid skin composition
S Blunder,1 R Rühl,2 D Orth-Höller3 and S Dubrac1 1Department of Dermatology, Venereology and Allergology, Innsbruck, Austria, 2Paprika Bioanalytics BT, Debrecen, Hungary and 3Department of Hygiene and Medical Bacteriology, Medical University of Innsbruck, Innsbruck, Austria
14.50-15.00 031 (Poster 189)
STAT1 gain-of-function compromises skin host defense in the context of IFN-γ signaling
H Niehues,1,2 B Rösler,3 D van der Krieken,1 I van Vlijmen-Willems,1 D Rodijk-Olthuis,1 M Peppelman,1 J Schalkwijk,1 P Zeeuwen,1,2 E van den Bogaard1,2 and F van de Veerdonk3 1Dermatology, Radboud University Medical Center, Nijmegen, Netherlands, 2Radboud Institute for Molecular Life Sciences, Nijmegen, Netherlands and 3Department of Internal Medicine, Radboudumc, Nijmegen, Netherlands
15.00-15.10 032 (Poster 194)
A CRISPR-interference screen identifies PRANCR and other novel long non-coding RNAs controlling human epidermis formation
A Otten,1 P Cai,2 B Cheng,1 M Ishii,1 K Qu2 and B Sun1 1Dermatology, University of California, San Diego, La Jolla, CA and 2School of Life Sciences, University of Science and Technology of China, Hefei, China
15.10-15.20 033 (Poster 274)
Junctional Epidermolysis Bullosa: Bottom Up Control Of The Skin Barrier?
EM Jones,1 S Marsh,1 RF O’Shaughnessy,1 E Camera,2 M Picardo,2 M Aumailley,3 E O’Toole1 and M Caley1 1Centre for Cutaneous Research, Blizard Institute, QMUL, London, United Kingdom, 2Istituto Dermatologico San Gallicano, Rome, Italy and 3Centre for Biochemistry, University of Cologne, Cologne, Germany
15.20-15.30 034 (Poster 239)
Desmosomes pattern cell mechanics to govern epidermal tissue form and function
JA Broussard, JL Koetsier and KJ Green Northwestern University, Chicago, IL
15.30-15.40 035 (Poster 268)
Geometry-dependent chromatin remodelling in keratinocytes is altered by cell-cell adhesions
LM Blowes, K Sliogeryte, N Gavara and J Connelly Queen Mary University of London, London, United Kingdom
15.40-15.50 036 (Poster 255)
Palmoplantar skin and keratinocytes harbouring mutant AQP5 display dysregulated actin cytoskeleton
D Blaydon and DP Kelsell Centre for Cell Biology and Cutaneous Research, Blizard Institute, QMUL, London, United Kingdom
15.50-16.00 037 (Poster 240)
SerpinB12 is an intrinsic mesotrypsin inhibitor regulating corneocyte desquamation and enucleation
M Miyai,1 J Hiruma,2 A Motoyama,1 M Egawa,1 M Yamamoto,2 Y Ozeki,3 R Tsuboi2 and T Hibino1,2 1Global Innovation Center, Shiseido, Yokohama, Kanagawa, Japan, 2Dermatology, Tokyo Medical University, Tokyo, Japan and 3Graduate School of Engineering, The University of Tokyo, Tokyo, Japan
16.00-16.10  038 (Poster 246)
Nuclear destruction during epidermal terminal differentiation requires actin cytoskeletonmediated nuclear lamin dispersal and rapid nuclear volume reduction
C Rogerson and RF O’Shaughnessy Blizard Institute, Queen Mary University of London, London, United Kingdom