Julia Reichelt

Julia Reichelt

Salzburg, Austria

Lecture Title: Gene editing for therapy of inherited skin diseases
Thursday 19 September 2019, time tba

Research interests
I am interested in the biology of skin in general and in inherited blistering skin disorders in particular.

My aim is to increase the knowledge in epidermolysis bullosa through research, develop treatments to improve the quality of life of patients and ultimately cure the disease.

Selected Recent Publications

Peking P, Koller U, Duarte B, Murillas R, Wolf S, Maetzig T, Rothe M, Kocher T, Garcia M, Brachtl G, Schambach A, Larcher F, Reichelt J , Bauer JW, Murauer EM. An RNA-targeted therapy for dystrophic epidermolysis bullosa. Nucleic Acids Res 2017; 45: 10259-69.
Kocher T, Peking P, Klausegger A, Murauer EM, Hofbauer JP, Wally V, Lettner T, Hainzl S, Ablinger M, Bauer JW, Reichelt J , Koller U. Cut and Paste: Efficient Homology-Directed Repair of a Dominant Negative KRT14 Mutation via CRISPR / Cas9 Nickases. Mol Ther 2017; 25: 2585-98.
Hirsch T, Rothoeft T, Dough N, Bauer JW, Pellegrini G, De Rosa L, Scaglione D, Reichelt J , Klausegger A, Kneisz D, Romano O, Secone Seconetti A, Contin R, Enzo E, Jurman I, Carulli S, Jacobsen F, Luecke T, Lehnhardt M, Fischer M, Kueckelhaus M, Quaglino D, Morgante M, Bicciato S, Bondanza S, De Luca M. Regeneration of the entire human epidermis using transgenic stem cells. Nature 2017; 551: 327-32.
Hainzl S, Peking P, Kocher T, Murauer EM, Larcher F, Del Rio M, Duarte B, Steiner M, Klausegger A, Bauer JW, Reichelt J , Koller U. COL7A1 Editing via CRISPR / Cas9 in Recessive Dystrophic Epidermolysis Bullosa. Mol Ther 2017; 25: 2573-84.
Aushev M, Koller U, C Mussolino, Cathomen T, Reichelt J . Traceless Targeting and Isolation of Gene-Edited Immortalized Keratinocytes from Epidermolysis Bullosa Simplex Patients. Mol Ther Methods Clin Dev 2017; 6: 112-23.

Frontiers in Skin Biology & Dermatology 1 & Plenary Session 1