Concurrent 2: Adaptive Immunity and Autoimmunity

Date: Thursday 23 September 2021
Time: 12.10-13.10 CET

 

Concurrent talks are 8 minutes plus 2 minutes discussion

Chairs

TBA

 

Program

12.10

ORAL 019 (POSTER 005)

PPAR-gamma promotes proliferation of pathogenic Th2 cells through regulation of IL-2 signaling

Fabian Luther1, Nicole L. Bertschi1, Oliver Steck1, Cecilia Bazzini1, Irene Keller2, Christoph Schlapbach1

1Dermatology, Inselspital, Bern University Hospital, Bern, Switzerland, 2Interfaculty Bioinformatics Unit and Swiss Institute of Bioinformatics, University of Bern, Bern, Switzerland

12.20

ORAL 020 (POSTER 020)

Sphingosine 1-phosphate receptor signalling promotes hair growth and inhibits perifollicular T-cell expansion and immune privilege collapse ex vivo

Ilaria Piccini1, Markus Fehrholz1, Onur Egriboz1, Leslie Ponce1, Alfredo Rossi2, Franzisco Jiminez3, John Adams4, Catherine M. Crosby4Marta Bertolini1

1Monasterium Laboratory GmbH, Muenster, Germany, 2Division of Dermatology, Department of Internal Medicine and Medical Specialties, Sapienza University of Rome, Rome, Italy, 3Mediteknia Hair Transplant Clinic and Hair Lab and Universidad Fernando Pessoa Canarias, Gran Canaria, Spain, 4Arena Pharmaceuticals, Inc, San Diego, California, United States

12.30

ORAL 021 (POSTER 003)

Anti-fractalkine monoclonal antibody therapy ameliorates murine sclerodermatous chronic graft-versus-host disease

Akira Utsunomiya1, Vu Huy Luong1, Takenao Chino1, Noritaka Oyama1, Takashi Matsushita2, naoto ishii3, Hideaki Ogasawara3, Imai Toshio3, Minoru Hasegawa1

1Dermatology, Fukui University, Eiheijicho, Fukui, Japan, 2Dermatology, Kanazawa University, Kanazawa, Japan, 3KAN Research Institute.Inc., Kobe, Japan

12.40

ORAL 022 (POSTER 013)

Unabated type I interferon expedites B-cell autoimmunity and anti-drug antibody formation during anti-TNF therapy

Anna Mennella1, 2, Alessio Mylonas1, Jiaqi Chen1, Alessia Nidegger1, Michel Gilliet1, Roberto Lande2, Loredana Frasca2, Curdin Conrad1

1CHUV, Lausanne, Switzerland, 2National Centre for Pre-Clinical and Clinical Drug Research&Evaluation, Istituto Superiore di Sanità, Rome, Italy

12.50

ORAL 023 (POSTER 122)

Pathogenic murine anti-BP230 autoantibody 20B12: Elucidating the mechanism of blister formation

Vanessa Bolduan1, Stefanie Haeberle1, Elisabeth Vicari1, Torben Ramcke1, Alexander Enk1, Eva Hadaschik1, 2

1Department of Dermatology, University Hospital Heidelberg, Heidelberg, Germany, 2Department of Dermatology, University Hospital Essen, Essen, Germany

13.10

ORAL 024 (POSTER 009)

Human desmocollin 3-specific IgG antibodies are pathogenic in a humanized HLA-class II transgenic mouse model of pemphigus

Christoph Hudemann1, Roberto Maglie1, Benedikt Beckert2, Dario Didona1, Thomas Schmitt3, Ritva Tikkanen2, Takashi Hashimoto4, Jens Waschke3, Michael Hertl1, Rüdiger Eming1

1Department of Dermatology and Allergology, Philipps-Universität Marburg, Marburg, Germany, 2Medical Faculty, University of Giessen, Institute of Biochemistry, Giessen, Germany, 3Ludwig-Maximilians-University, Institute of Anatomy and Cell Biology, München, Germany, 4Department of Dermatology, Osaka City University Graduate School of Medicine, Osaka, Japan