Concurrent 6: Genetics, Stem Cells, Skin Appendages and Tissue Regeneration

Date: Friday 24 September 2021
Time: 12.10-13.10 CET

 

Concurrent talks are 8 minutes plus 2 minutes discussion

Chairs

Caterina Missero (Naples), Neil Rajan (Newcastle-upon-Tyne)

 

Program

12.10

ORAL 043 (POSTER 161)

Nucleolar TFIIE plays a role in ribosomal biogenesis and performance

Tamara Phan1, Pallab Maity1, Christina Ludwig2, Lisa Streit3, Jens Michaelis3, Karin Schaffetter-Kochanek1, Sebastian Iben1

1Dermatology and Allergology, University Hospital Ulm, Ulm, Germany, 2Bavarian Center for Biomolecular Mass Spectrometry, Technical University Munich, Munich, Bavaria, Germany, 3Biophysics, University Ulm, Ulm, Germany

12.20

ORAL 044 (POSTER 156)

Targeted ex-vivo correction of COL7A1 through RNP-based CRISPR/Cas9 and Homology-Directed Repair to treat recessive dystrophic epidermolysis bullosa

Araksya Izmiryan1, Camille Berthault1, Olivier Gouin1, Mei Chen2, David Woodley3, Sonia Gaucher1, Alain Hovnanian1

1INSERM 1163-Imagine Institute, Paris, France, 2Norris Comprehensive Cancer Center, Los Angeles, California, United States, 3The Keck School of Medicine, Los Angeles, California, United States

12.30

ORAL 045 (POSTER 324)

Improvement of epidermal covering on AEC patients with severe skin erosions by PRIMA-1MET

Edith Aberdam2, 3, Lauriane N. Roux2, 3, Philippe-Henri Secrétan4, 5, Franck Boralevi6, Joel Schlatter4, Fanny Morice-Picard6, Stefano Sol7, 8, Christine Bodemer1, 9, 10, Caterina Missero7, 8, Salvatore Cisternino4, 11, Daniel Aberdam2, 3Smail Hadj-Rabia1, 9, 10

1Dermatology, APHP, Necker-ENfants Malades Hospital, Paris, France, 2INSERM U976, Paris, France, 3Université Paris-Diderot, Paris, France, 4Pharmacy, APHP, Necker-ENfants Malades Hospital, Paris, France, 5Faculté de Pharmacie, Chatenay Malabry, France, 6Dermatology, CHU Pellegrin, Bordeaux, France, 7CEINGE, Napoli, Italy, 8University of Naples Federico II, Napoli, Italy, 9Université de Paris-Centre, Paris, France, 10Institut Imagine, Paris, France, 11Faculté de Pharmacie de Paris, INSERM U1144, Paris, France

 

12.40

ORAL 046 (POSTER 321)

Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia

Ann-Helen S. Rosendahl1, Mia Monnius1, Anu Laitala1, Antti Railo1, Ilkka Miinalainen2, Ritva Heljasvaara1, Joni M. Mäki1, Johanna Myllyharju1

1Oulu Center for Cell-Matrix Research, Faculty of Biochemistry and Molecular Medicine, University of Oulu, Oulu, Finland, 2Biocenter Oulu, University of Oulu, Oulu, Finland

12.50

ORAL 047 (POSTER 318)

The Wnt-inhibitor Dkk4 is required for primary hair follicle induction and patterning

Houda Khatif2, 1, Hisham Bazzi2, 1

1CECAD Excellence Cluster, University of Cologne, Cologne, Germany, 2Dermatology & Venerology, University of Cologne, Cologne, Germany

13.10

ORAL 048 (POSTER 320)

Desmoglein 3-mediated mechanical transadhesion controls epithelial stem cell quiescence

William V. Hariton2, Katja Schulze3, Andrew Overmiller4, My G. Mahoney4, Luca Borradori1, Beyza S. Sayar2, Arnaud Galichet1Eliane J. Müller1, 2, 3

1Dermatology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland, 2Biomedical Research, University of Bern, Bern, Switzerland, 3Institute Animal Pathology, University of Bern, Bern, Switzerland, 4Dermatology and Cutaneous Biology, Thomas Jefferson University, Philadelphia, Pennsylvania, United States