PROGRAM

[ABSTRACT 172]

CYSRT1: an antimicrobial epidermal protein that interacts with late cornified envelope (LCE) proteins

H Niehues, G Rikken, F Kersten, J Eeftens, M Oortveld, D van der krieken, P Jansen, IM van Vlijmen-Willems, JP Smits, N van den Brink, W Hendriks, T Ederveen, J Schalkwijk, PL Zeeuwen and EH van den Bogaard Dermatology, Radboudumc, Nijmegen, Netherlands

[ABSTRACT 184]

The role of the Laminin 332 in cholesterol transport in dry and Aged skin

P Parzymies,¹ E Jones,¹ MP Caley,¹ EA O’Toole,¹ D Messenger² and A Mayes^{2 1} Blizard Institute, Queen Mary University of London, London, United Kingdom and ² Research and Development, Unilever, Colworth, United Kingdom

[ABSTRACT 548]

Deletion of Myelin Protein Zero-like 3 increases sebaceous gland size and sebocyte proliferation but reduces skin adipose depots: Can MPZL3 inhibition promote excessive loss of lipids via sebum hypersecretion?

TC Wikramanayake, C Nicu, J Gherardini, T Suzuki, J Chéret and R Paus Dr. Phillip Frost Department of Dermatology & Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL

[ABSTRACT 174]

Defining the composition and function of Lamin ribonuclear bodies during keratinocyte terminal differentiation and nuclear degradation

DJ Wotherspoon, T Tachie-Menson, C Rogerson and R O’Shaughnessy Centre for Cell Biology and Cutaneous Research, Queen Mary University of London, London, United Kingdom

[ABSTRACT 175]

Yap and Notch signaling activities correlate with the two phases of skin epidermal stratification during development

L Wirtz,¹ M Damen,¹ H Khatif,¹ E Soroka,¹ B Simons² and H Bazzi^{1 1} Dermatology, University Hospital Cologne, Cologne, Germany and ² The Welcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, United Kingdom

[ABSTRACT 178]

The LRRC8 ion channel as novel drug target for psoriasis

T Fauth,¹ M Jahn,² O Rauh³ and C Buerger^{2 1} BRAIN Biotech AG, Zwingenberg, Germany, ² Department of Dermatology, University Hospital Frankfurt, Frannkfurt, Germany and ³ Membrane Biophysics, Technische Universität Darmstadt, Darmstadt, Germany

[ABSTRACT 179]

Oxidative Damage is a Hallmark of Atopic Dermatitis in Humans and Mice

M Koch,¹ E Rodriguez,² U Wehkamp,² H Beer,³ E Tschachler,⁴ S Weidinger,² U auf dem Keller⁵ and S Werner^{1 1} ETH Zurich, Zurich, Switzerland, ² University Hospital Schleswig-Holstein, Kiel, Germany, ³ University Hospital Zurich, Zurich, Switzerland, ⁴ Medical University of Vienna, Vienna, Austria and ⁵ Technical University of Denmark, Lyngby, Denmark

[ABSTRACT 173]

A Model to Unravel Pathways Underpinning Palmoplantar Homeostasis and Disease

S Murtough,¹ L Ramos Del Cano,¹ PJ Delaney,¹ CM Webb,¹ B Colom,² PH Jones,² D Blaydon¹ and D Kelsell^{1 1} Queen Mary University of London, London, United Kingdom and ² Wellcome Sanger Institute, Cambridge, United Kingdom