Concurrent 1: Epidermal Structure and Function

Date: Thursday 29 September 2022
Time: 15.00-16.30

Room:

Chairs:

Concurrent talks are 8 minutes plus 2 minutes discussion

 

PROGRAM

 

 

15.00-15.10

[ABSTRACT 172]

CYSRT1: an antimicrobial epidermal protein that interacts with late cornified envelope (LCE) proteins

H Niehues, G Rikken, F Kersten, J Eeftens, M Oortveld, D van der krieken, P Jansen, IM van Vlijmen-Willems, JP Smits, N van den Brink, W Hendriks, T Ederveen, J Schalkwijk, PL Zeeuwen and EH van den Bogaard Dermatology, Radboudumc, Nijmegen, Netherlands

 

15.10-15.20

[ABSTRACT 184]

The role of the Laminin 332 in cholesterol transport in dry and Aged skin

P Parzymies,1 E Jones,1 MP Caley,1 EA O’Toole,1 D Messenger2 and A Mayes2 1 Blizard Institute, Queen Mary University of London, London, United Kingdom and 2 Research and Development, Unilever, Colworth, United Kingdom

 

15.20-15.30

[ABSTRACT 548]

Deletion of Myelin Protein Zero-like 3 increases sebaceous gland size and sebocyte proliferation but reduces skin adipose depots: Can MPZL3 inhibition promote excessive loss of lipids via sebum hypersecretion?

TC Wikramanayake, C Nicu, J Gherardini, T Suzuki, J Chéret and R Paus Dr. Phillip Frost Department of Dermatology & Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL

 

15.30-15.40

[ABSTRACT 174]

Defining the composition and function of Lamin ribonuclear bodies during keratinocyte terminal differentiation and nuclear degradation

DJ Wotherspoon, T Tachie-Menson, C Rogerson and R O’Shaughnessy Centre for Cell Biology and Cutaneous Research, Queen Mary University of London, London, United Kingdom

 

15.40-15.50

[ABSTRACT 175]

Yap and Notch signaling activities correlate with the two phases of skin epidermal stratification during development

L Wirtz,1 M Damen,1 H Khatif,1 E Soroka,1 B Simons2 and H Bazzi1 1 Dermatology, University Hospital Cologne, Cologne, Germany and 2 The Welcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, United Kingdom

 

15.50-16.00

[ABSTRACT 178]

The LRRC8 ion channel as novel drug target for psoriasis

T Fauth,1 M Jahn,2 O Rauh3 and C Buerger2 1 BRAIN Biotech AG, Zwingenberg, Germany, 2 Department of Dermatology, University Hospital Frankfurt, Frannkfurt, Germany and 3 Membrane Biophysics, Technische Universität Darmstadt, Darmstadt, Germany

 

16.00-16.10

[ABSTRACT 179]

Oxidative Damage is a Hallmark of Atopic Dermatitis in Humans and Mice

M Koch,1 E Rodriguez,2 U Wehkamp,2 H Beer,3 E Tschachler,4 S Weidinger,2 U auf dem Keller5 and S Werner1 1 ETH Zurich, Zurich, Switzerland, 2 University Hospital Schleswig-Holstein, Kiel, Germany, 3 University Hospital Zurich, Zurich, Switzerland, 4 Medical University of Vienna, Vienna, Austria and 5 Technical University of Denmark, Lyngby, Denmark

 

16.10-16.20

[ABSTRACT 173]

A Model to Unravel Pathways Underpinning Palmoplantar Homeostasis and Disease

S Murtough,1 L Ramos Del Cano,1 PJ Delaney,1 CM Webb,1 B Colom,2 PH Jones,2 D Blaydon1 and D Kelsell1 1 Queen Mary University of London, London, United Kingdom and 2 Wellcome Sanger Institute, Cambridge, United Kingdom