PROGRAM

[ABSTRACT 001]

Effector functions of human TH9 cells depend on PPARγ-regulated glucose metabolism

F Luther,¹ O Steck,¹ NL Bertschi,¹ C Bazzini,¹ I Keller,² D Simon¹ and C Schlapbach^{1 1} Dermatology, University Hospital Bern, Inselspital, Bern, Switzerland and ² Interfaculty Bioinformatics Unit and Swiss Institute of Bioinformatics, University of Bern, Bern, Switzerland

[ABSTRACT 006]

Conventional dendritic cell 2 as an activator for cytotoxic T lymphocytes in the elicitation phase of murine contact hypersensitivity

F Minami,¹ R Asahina,¹ S Ono,¹ T Honda,² G Egawa,¹ S Nakamizo¹ and K Kabashima^{1 1} Dermatology, Graduate School of Medicine Kyoto University, Kyoto city, Japan and ² Dermatology, Hamamatsu University School of Medicine, Hamamatsu, Japan

[ABSTRACT 015]

Clonal sharing of skin T cells within different skin compartments and blood

E Hoffer^1,2, W Zheng,^1,2, J Kärner, M Ehrström³, L Eidsmo^{1,2 1}Leo Foundation Skin Immunology Center, Department of Microbiology and Immunology, University of Copenhagen, Denmark ²Division of Rheumatology, Department of Medicine, Karolinska Institute, Sweden ³Nordiska Kliniken, Stockholm, Sweden 

[ABSTRACT 007]

Antibodies to the BP180 C-terminus cause autoimmune blistering disease through activation of the C5a/C5aR1 axis and Fcγ receptors

M Pigors,¹ S Patzelt,¹ N Reichhelm,¹ S Emtenani,¹ J Dworschak,² K Bieber,¹ S Goletz,¹ L Komorowski,² C Probst,² J K.öhl¹ and E Schmidt1 ¹ University of Lübeck, Lübeck, Germany and ² EUROIMMUN AG, Lübeck, Germany

[ABSTRACT 011]

Targeted inhibition of complement C3 deposition at the basement membrane zone in pemphigoid disease

CM Hammers,¹ S Emtenani,² A Khodr El-Oueyk,¹ C Papara,² O Isken,³ N Tautz,³ C Lin,⁴ JE Hundt,² A Verschoor,¹ D Zillikens,¹ E Schmidt,^2,1 DL Siegel⁵ and JR Stanley^{4 1} Derm, U Luebeck, Luebeck, Germany, ² LIED, U Luebeck, Luebeck, Germany, ³ Virol, U Luebeck, Luebeck, Germany, ⁴ Derm, UPENN, Phila, PA and ⁵ Path Lab Med, UPENN, Phila, PA

[ABSTRACT 322]

Type 2 cytokines regulate dermal adipocyte function early in life through hormone-sensitive lipase

S Satzinger,¹ S Willenborg,¹ X Ding,¹ D Voehringer² and SA Eming^{1 1} Dermatology, University of Cologne, Cologne, Germany and ² Infection Biology, University Hospital Erlangen and Friedrich-Alexander University Erlangen-Nuremberg (FAU), Erlangen, Germany

[ABSTRACT 323]

A Novel, Stress-Responsive and Clinically Predictive Humanized Mouse Model of Atopic Dermatitis: Autologous Th2-Polarized Lymphocytes Suffice to Induce Characteristic Lesions in Healthy Non-Atopic Human Skin Xenotransplants In Vivo

R Paus,¹ A Keren,² K Reich,³ M Bertolini,⁴ C Riethmüller,⁵ Y Ullmann² and A Gilhar^{2 1} Dermatology, University of Miami, Miami, FL, ² Technion–Israel Institute of Technology, Haifa, Israel, ³ Institute for Health Care Research in Dermatology and Nursing, University Medical Center Hamburg – Eppendorf, Hamburg, Germany, ⁴ Monasterium Laboratory, Münster, Germany and ⁵ Serendip GmbH, Münster, Germany

[ABSTRACT 004]

Cell-based therapy may be effective in alopecia areata: Preclinical evidence that autologous, peripheral regulatory γdT cells are preventive in human ex vivo and therapeutic in human in vivo models

A Keren,¹ M Bertolini,² R Paus³ and A Gilhar^{1 1} Technion, Haifa, Israel, ² Monasterium, Munster, Germany and ³ University of Miami, Miami, FL