Concurrent 2: Adaptive Immunity and Autoimmunity

Date: Thursday 29 September 2022
Time: 15.00-16.30

Room:

Chairs:

Concurrent talks are 8 minutes plus 2 minutes discussion

 

PROGRAM

 

 

15.00-15.10

[ABSTRACT 001]

Effector functions of human TH9 cells depend on PPARγ-regulated glucose metabolism

F Luther,1 O Steck,1 NL Bertschi,1 C Bazzini,1 I Keller,2 D Simon1 and C Schlapbach1 1 Dermatology, University Hospital Bern, Inselspital, Bern, Switzerland and 2 Interfaculty Bioinformatics Unit and Swiss Institute of Bioinformatics, University of Bern, Bern, Switzerland

 

15.10-15.20

[ABSTRACT 006]

Conventional dendritic cell 2 as an activator for cytotoxic T lymphocytes in the elicitation phase of murine contact hypersensitivity

F Minami,1 R Asahina,1 S Ono,1 T Honda,2 G Egawa,1 S Nakamizo1 and K Kabashima1 1 Dermatology, Graduate School of Medicine Kyoto University, Kyoto city, Japan and 2 Dermatology, Hamamatsu University School of Medicine, Hamamatsu, Japan

 

15.20-15.30

[ABSTRACT 015]

Clonal sharing of skin T cells within different skin compartments and blood

E Hoffer1,2 1 Dept Immuno- and Microbiology, University of Copenhagen, Stockholm, Sweden and 2 Department of Medicine, Karolinska Institute, Stockholm, Sweden

 

15.30-15.40

[ABSTRACT 007]

Antibodies to the BP180 C-terminus cause autoimmune blistering disease through activation of the C5a/C5aR1 axis and Fcγ receptors

M Pigors,1 S Patzelt,1 N Reichhelm,1 S Emtenani,1 J Dworschak,2 K Bieber,1 S Goletz,1 L Komorowski,2 C Probst,2 J K.öhl1 and E Schmidt1 1 University of Lübeck, Lübeck, Germany and 2 EUROIMMUN AG, Lübeck, Germany

 

15.40-15.50

[ABSTRACT 011]

Targeted inhibition of complement C3 deposition at the basement membrane zone in pemphigoid disease

CM Hammers,1 S Emtenani,2 A Khodr El-Oueyk,1 C Papara,2 O Isken,3 N Tautz,3 C Lin,4 JE Hundt,2 A Verschoor,1 D Zillikens,1 E Schmidt,2,1 DL Siegel5 and JR Stanley4 1 Derm, U Luebeck, Luebeck, Germany, 2 LIED, U Luebeck, Luebeck, Germany, 3 Virol, U Luebeck, Luebeck, Germany, 4 Derm, UPENN, Phila, PA and 5 Path Lab Med, UPENN, Phila, PA

 

15.50-16.00

[ABSTRACT 322]

Type 2 cytokines regulate dermal adipocyte function early in life through hormone-sensitive lipase

S Satzinger,1 S Willenborg,1 X Ding,1 D Voehringer2 and SA Eming1 1 Dermatology, University of Cologne, Cologne, Germany and 2 Infection Biology, University Hospital Erlangen and Friedrich-Alexander University Erlangen-Nuremberg (FAU), Erlangen, Germany

 

16.00-16.10

[ABSTRACT 323]

A Novel, Stress-Responsive and Clinically Predictive Humanized Mouse Model of Atopic Dermatitis: Autologous Th2-Polarized Lymphocytes Suffice to Induce Characteristic Lesions in Healthy Non-Atopic Human Skin Xenotransplants In Vivo

R Paus,1 A Keren,2 K Reich,3 M Bertolini,4 C Riethmüller,5 Y Ullmann2 and A Gilhar2 1 Dermatology, University of Miami, Miami, FL, 2 Technion–Israel Institute of Technology, Haifa, Israel, 3 Institute for Health Care Research in Dermatology and Nursing, University Medical Center Hamburg – Eppendorf, Hamburg, Germany, 4 Monasterium Laboratory, Münster, Germany and 5 Serendip GmbH, Münster, Germany

 

16.10-16.20

[ABSTRACT 004]

Cell-based therapy may be effective in alopecia areata: Preclinical evidence that autologous, peripheral regulatory γdT cells are preventive in human ex vivo and therapeutic in human in vivo models

A Keren,1 M Bertolini,2 R Paus3 and A Gilhar1 1 Technion, Haifa, Israel, 2 Monasterium, Munster, Germany and 3 University of Miami, Miami, FL