Concurrent 2: Adaptive Immunity and Autoimmunity

Date: Thursday 29 September 2022
Time: 15.00-16.30

Room 2

Chairs: Curdin Conrad (Lausanne), Bernhard Homey (Düsseldorf)

Concurrent talks are 8 minutes plus 2 minutes discussion







Effector functions of human TH9 cells depend on PPARγ-regulated glucose metabolism

F Luther,1 O Steck,1 NL Bertschi,1 C Bazzini,1 I Keller,2 D Simon1 and C Schlapbach1 1 Dermatology, University Hospital Bern, Inselspital, Bern, Switzerland and 2 Interfaculty Bioinformatics Unit and Swiss Institute of Bioinformatics, University of Bern, Bern, Switzerland




Conventional dendritic cell 2 as an activator for cytotoxic T lymphocytes in the elicitation phase of murine contact hypersensitivity

F Minami,1 R Asahina,1 S Ono,1 T Honda,2 G Egawa,1 S Nakamizo1 and K Kabashima1 1 Dermatology, Graduate School of Medicine Kyoto University, Kyoto city, Japan and 2 Dermatology, Hamamatsu University School of Medicine, Hamamatsu, Japan




Clonal sharing of skin T cells within different skin compartments and blood

E Hoffer1,2, W Zheng,1,2, J Kärner, M Ehrström3, L Eidsmo1,2 1Leo Foundation Skin Immunology Center, Department of Microbiology and Immunology, University of Copenhagen, Denmark 2Division of Rheumatology, Department of Medicine, Karolinska Institute, Sweden 3Nordiska Kliniken, Stockholm, Sweden 




Antibodies to the BP180 C-terminus cause autoimmune blistering disease through activation of the C5a/C5aR1 axis and Fcγ receptors

M Pigors,1 S Patzelt,1 N Reichhelm,1 S Emtenani,1 J Dworschak,2 K Bieber,1 S Goletz,1 L Komorowski,2 C Probst,2 J K.öhl1 and E Schmidt1 1 University of Lübeck, Lübeck, Germany and 2 EUROIMMUN AG, Lübeck, Germany




Targeted inhibition of complement C3 deposition at the basement membrane zone in pemphigoid disease

CM Hammers,1 S Emtenani,2 A Khodr El-Oueyk,1 C Papara,2 O Isken,3 N Tautz,3 C Lin,4 JE Hundt,2 A Verschoor,1 D Zillikens,1 E Schmidt,2,1 DL Siegel5 and JR Stanley4 1 Derm, U Luebeck, Luebeck, Germany, 2 LIED, U Luebeck, Luebeck, Germany, 3 Virol, U Luebeck, Luebeck, Germany, 4 Derm, UPENN, Phila, PA and 5 Path Lab Med, UPENN, Phila, PA




Type 2 cytokines regulate dermal adipocyte function early in life through hormone-sensitive lipase

S Satzinger,1 S Willenborg,1 X Ding,1 D Voehringer2 and SA Eming1 1 Dermatology, University of Cologne, Cologne, Germany and 2 Infection Biology, University Hospital Erlangen and Friedrich-Alexander University Erlangen-Nuremberg (FAU), Erlangen, Germany




A Novel, Stress-Responsive and Clinically Predictive Humanized Mouse Model of Atopic Dermatitis: Autologous Th2-Polarized Lymphocytes Suffice to Induce Characteristic Lesions in Healthy Non-Atopic Human Skin Xenotransplants In Vivo

R Paus,1 A Keren,2 K Reich,3 M Bertolini,4 C Riethmüller,5 Y Ullmann2 and A Gilhar2 1 Dermatology, University of Miami, Miami, FL, 2 Technion–Israel Institute of Technology, Haifa, Israel, 3 Institute for Health Care Research in Dermatology and Nursing, University Medical Center Hamburg – Eppendorf, Hamburg, Germany, 4 Monasterium Laboratory, Münster, Germany and 5 Serendip GmbH, Münster, Germany




Cell-based therapy may be effective in alopecia areata: Preclinical evidence that autologous, peripheral regulatory γdT cells are preventive in human ex vivo and therapeutic in human in vivo models

A Keren,1 M Bertolini,2 R Paus3 and A Gilhar1 1 Technion, Haifa, Israel, 2 Monasterium, Munster, Germany and 3 University of Miami, Miami, FL