Concurrent 3: Wound Healing and Tissue Remodelling

Date: Thursday 29 September 2022
Time: 15.00-16.30

Room 3

Chairs: Emanuel Rognoni (London), Enikö Sonkoly (Stockholm)

Concurrent talks are 8 minutes plus 2 minutes discussion







Exploring the molecular basis for the dermal fibroblast state switch

T Kirk, A Ahmed, J Connelly and E Rognoni Queen Mary University of London, London, United Kingdom




Elucidating the role of Circular RNA circGLIS3 in human skin wound healing

M Toma, G Niu, J Geara and NX Landén Karolinska Institute, Solna, Sweden




Healthy repair of injured skin requires mitochondrial repurposing in wound macrophages

S Willenborg,1 DE Sanin,2 A Jais,3 JL Schultze,4 A Roers,5 EJ Pearce,6 JC Brüning,3 A Trifunovic7 and SA Eming1 1 Dermatology, University of Cologne, Cologne, Germany, 2 MPI Epigenetics and Immunobiology, Freiburg, Germany, 3 MPI Metabolism Research, Cologne, Germany, 4 LIMES-Institute, Bonn, Germany, 5 Immunology, TU Dresden, Dresden, Germany, 6 MPI Epigenetics and Immunobiology, Cologne, Germany and 7 CECAD, University of Cologne, Cologne, Germany




aPKC is a rheostat that controls basal junctional dynamics and suprabasal cytoskeletal organization essential for epidermal dynamics and integrity

M Rübsam,1 R Püllen,2 F Telkamp,3 A Bianco,1 M Pescoller,1 W Bloch,4 KJ Green,5 R Merkel,2 B Hoffmann,2 S Wickström6 and C Niessen1 1 Department Cell Biology of the Skin, Universityof Cologne, Cologne, Germany, 2 Institute of Complex Systems, Forschungszentrum Jülich, Jülich, Germany, 3 Institute for Genetics, University of Cologne, Cologne, Germany, 4 Department of Molecular and Cellular Sport Medicine, German Sport University of Cologne, Cologne, Germany, 5 Department of Dermatology, Northwestern University, Chicago, IL and 6 Stem Cells and Metabolism Research Program, University of Helsinki, Helsinki, Finland




Ribosome heterogeneity by rRNA methylation in skin cell senescence

G Yang,1,4 F Nagelreiter,1 M Schmid-Siegel,2,1 C Heissenberger1 and M Schosserer2,1,3 1 Institute of Molecular Biotechnology, Department of Biotechnology, University of Natural Resources and Life Sciences, Vienna, Vienna, Austria, 2 CD Laboratory for Multimodal Imaging of Aging and Senescence of the Skin, Medical University of Vienna, Vienna, Austria, 3 Austrian Cluster for Tissue Regeneration, Vienna, Austria and 4 Biochemistry Center (BZH), Heidelberg University, Heidelberg, Germany




Hippo pathway drives excessive fibrosis in Hidradenitis Suppurativa

KR van Straalen,1 F Ma,2 M Calbet,3 M Gharaee-Kermani,1,2 R Wasikowski,1 AC Billi,1 E Tsou,2 LC Tsoi1 and J Gudjonsson1 1 Dept of Dermatology, University of Michigan Medical School, Ann Arbor, MI, 2 Div of Rheumatology, Dept of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI and 3 R&D Center, Almirall SA, Sant Feliu de Llobregat, Spain




Epigenetic memory of radiation injury in skin fibroblasts of cancer patients

MM Piipponen,1 X Bian,1 Z Liu,1 M Maselli,2 P Sommar,3 M Halle3 and NX Landén1 1 Department of Medicine Solna, Karolinska Institutet, Solna, Sweden, 2 University of Trieste, Trieste, Italy and 3 Plastic and Reconstructive Surgery, Karolinska University Hospital, Stockholm, Sweden




Type I interferon contributes to vasculopathy and accelerated fibrosis in systemic sclerosis

H Yin, Q Yan and L Lu Rheumatology, Shanghai Jiao Tong University School of Medicine Affiliated Renji Hospital, Shanghai, China