PROGRAM

[ABSTRACT 591]

Exploring the molecular basis for the dermal fibroblast state switch

T Kirk, A Ahmed, J Connelly and E Rognoni Queen Mary University of London, London, United Kingdom

[ABSTRACT 596]

Elucidating the role of Circular RNA circGLIS3 in human skin wound healing

M Toma, G Niu, J Geara and NX Landén Karolinska Institute, Solna, Sweden

[ABSTRACT 317]

Healthy repair of injured skin requires mitochondrial repurposing in wound macrophages

S Willenborg,¹ DE Sanin,² A Jais,³ JL Schultze,⁴ A Roers,⁵ EJ Pearce,⁶ JC Brüning,³ A Trifunovic⁷ and SA Eming^{1 1} Dermatology, University of Cologne, Cologne, Germany, ² MPI Epigenetics and Immunobiology, Freiburg, Germany, ³ MPI Metabolism Research, Cologne, Germany, ⁴ LIMES-Institute, Bonn, Germany, ⁵ Immunology, TU Dresden, Dresden, Germany, ⁶ MPI Epigenetics and Immunobiology, Cologne, Germany and ⁷ CECAD, University of Cologne, Cologne, Germany

[ABSTRACT 185]

aPKC is a rheostat that controls basal junctional dynamics and suprabasal cytoskeletal organization essential for epidermal dynamics and integrity

M Rübsam,¹ R Püllen,² F Telkamp,³ A Bianco,¹ M Pescoller,¹ W Bloch,⁴ KJ Green,⁵ R Merkel,² B Hoffmann,² S Wickström⁶ and C Niessen^1 1 Department Cell Biology of the Skin, Universityof Cologne, Cologne, Germany, ² Institute of Complex Systems, Forschungszentrum Jülich, Jülich, Germany, ³ Institute for Genetics, University of Cologne, Cologne, Germany, ⁴ Department of Molecular and Cellular Sport Medicine, German Sport University of Cologne, Cologne, Germany, ⁵ Department of Dermatology, Northwestern University, Chicago, IL and ⁶ Stem Cells and Metabolism Research Program, University of Helsinki, Helsinki, Finland

[ABSTRACT 271]

Ribosome heterogeneity by rRNA methylation in skin cell senescence

G Yang,^1,4 F Nagelreiter,¹ M Schmid-Siegel,^2,1 C Heissenberger¹ and M Schosserer^{2,1,3 1} Institute of Molecular Biotechnology, Department of Biotechnology, University of Natural Resources and Life Sciences, Vienna, Vienna, Austria, ² CD Laboratory for Multimodal Imaging of Aging and Senescence of the Skin, Medical University of Vienna, Vienna, Austria, ³ Austrian Cluster for Tissue Regeneration, Vienna, Austria and ⁴ Biochemistry Center (BZH), Heidelberg University, Heidelberg, Germany

[ABSTRACT 594]

Hippo pathway drives excessive fibrosis in Hidradenitis Suppurativa

KR van Straalen,¹ F Ma,² M Calbet,³ M Gharaee-Kermani,^1,2 R Wasikowski,¹ AC Billi,¹ E Tsou,² LC Tsoi¹ and J Gudjonsson^{1 1} Dept of Dermatology, University of Michigan Medical School, Ann Arbor, MI, ² Div of Rheumatology, Dept of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI and ³ R&D Center, Almirall SA, Sant Feliu de Llobregat, Spain

[ABSTRACT 592]

Epigenetic memory of radiation injury in skin fibroblasts of cancer patients

MM Piipponen,¹ X Bian,¹ Z Liu,¹ M Maselli,² P Sommar,³ M Halle³ and NX Landén^1 1 Department of Medicine Solna, Karolinska Institutet, Solna, Sweden, ² University of Trieste, Trieste, Italy and ³ Plastic and Reconstructive Surgery, Karolinska University Hospital, Stockholm, Sweden

[ABSTRACT 595]

Type I interferon contributes to vasculopathy and accelerated fibrosis in systemic sclerosis

H Yin, Q Yan and L Lu Rheumatology, Shanghai Jiao Tong University School of Medicine Affiliated Renji Hospital, Shanghai, China