Concurrent 4: Innate Immunity and Inflammation

Date: Friday 30 September 2022
Time: 16.30-18.00

Room 1

Chairs: Paolo DiMeglio (London), Christoph Schlapbach (Bern)

Concurrent talks are 8 minutes plus 2 minutes discussion

PROGRAM

 

 

16.30-16.40

[ABSTRACT 318]
The long non-coding RNA LINC00958 is overexpressed in psoriasis epidermis and induces keratinocyte proliferation

L Luo,1,2,3 L Pasquali,1,3 A Srivastava,1,3,4 A Pivarcsi1,3,5 and E Sonkoly1,3 1Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden, 2Department of Medical Sciences, Uppsala University, Uppsala, Sweden, 3Center for Molecular Medicine (CMM), Karolinska University Hospital, Stockholm, Sweden, 4The Program in Epithelial Biology, Stanford University School of Medicine, California, USA, CA and 5Department of Medical Biochemistry and Microbiology (IMBIM), Uppsala University, Uppsala, Sweden

 

16.40-16.50

[ABSTRACT 324]
Skin Microbiota Activate the Aryl Hydrocarbon Receptor via Tryptophan Metabolism

AE Elias,1 AJ McBain2 and CA O’Neill1 1Division of Musculoskeletal and Dermatological Sciences, University of Manchester, Manchester, United Kingdom and 2 Division of Pharmacy and Optometry, University of Manchester, Manchester, United Kingdom

 

16.50-17.00

[ABSTRACT 180]
The antimicrobial peptide derived from insulin-like growth factor-binding protein 5 promotes skin barrier function and relieves dermatitis-like symptoms in a mouse model of atopic dermatitis

HL Nguyen,2,1 G Peng,2,1 J Jujillo-Paez,2 H Yue,2 K Okumura,2 H Ogawa,2 S Ikeda2 and F Niyonsaba2,3 1 Dermatology and Allergology, Juntendo Daigaku, Tokyo, Japan, 2 Atopy (Allergy) Research Center, Juntendo University, Tokyo, Japan and 3 Faculty of International Liberal Arts, Juntendo University, Tokyo, Japan

 

17.00-17.10

[ABSTRACT 546]
Epidermal growth factor receptor as a key regulator of the immune privilege

K Strobl, R Jin, L Artner, J Klufa, M Sibilia and T Bauer Center for Cancer Research, Medical University of Vienna, Vienna, Austria

 

17.10-17.20

[ABSTRACT 436]
Keratinocyte Regnase-1, a down-modulator of skin inflammation, contributes to protection from carcinogenesis through regulating COX-2

H Morisaka,1 M Takaishi,1 S Akira2,3 and S Sano1  1Dermatology, Kochi Medical School, Kochi University, Kochi, Japan, 2 Laboratory of Host Defence, World Premier Institute Immunology Frontier Research Center, Osaka University, Suita, Japan and 3 Department of Host Defence, Research Institute for Microbial Diseases, Osaka University, Suita, Japan

 

17.20-17.30

[ABSTRACT 330]
Poly(ADP-ribose) polymerase (PARP)-2 promotes inflammation in psoriasis by regulating estradiol biosynthesis in keratinocytes

D Antal,1 A Par,3 K Hegyi,2 I Kovacs,3 A Szegedi,2 P Bai1,4,5 and M Szanto1Department of Medical Chemistry, University of Debrecen, Debrecen, Hungary, 2 Department of Dermatology, University of Debrecen, Debrecen, Hungary, 3 Department of Pathology, University of Debrecen, Kenézy Gyula Campus, Debrecen, Hungary, 4 MTA-DE Lendület Laboratory of Cellular Metabolism, University of Debrecen, Debrecen, Hungary and 5 Research Center for Molecular Medicine, University of Debrecen, Debrecen, Hungary

 

17.30-17.40

[ABSTRACT 331]
Mitochondrial stress contributes to atopic dermatitis

DC Minzaghi,1 P Pavel,1 G Leman,1 F Gruber,2 S Oberreiter,1 S Blunder,1 R Gruber1 and S Dubrac1Department of dermatology, Medical University of Innsbruck, Austria, Innsbruck, Austria and 2 Dermatology, Medical University Vienna, Vienna, Austria

 

17.40-17.50

[ABSTRACT 319]
S. aureus can induce NLRP1 inflammasome activation in patients with atopic dermatitis

H Vaher,1 K Kingo,1 P Kolberg,1 K Alasoo,1 L Raam,2 T Tenson,1 U Mrowietz,3 S Weidinger,3 K Kingo2 and A Rebane1University of Tartu, Tartu, Estonia, 2 Tartu University Hospital, Tartu, Estonia and 3 Christian-Albrechts-University of Kiel, Kiel, Germany