Concurrent 4: Innate Immunity and Inflammation

Date: Friday 30 September 2022
Time: 16.30-18.00

Room:

Chairs

Concurrent talks are 8 minutes plus 2 minutes discussion

 

PROGRAM

 

 

16.30-16.40

[ABSTRACT 318]

The long non-coding RNA LINC00958 is overexpressed in psoriasis epidermis and induces keratinocyte proliferation

L Luo,1,2,3 L Pasquali,1,3 A Srivastava,1,3,4 A Pivarcsi1,3,5 and E Sonkoly1,3,2 1 Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden, 2 Department of Medical Sciences, Uppsala University, Uppsala, Sweden, 3 Center for Molecular Medicine (CMM), Karolinska University Hospital, Stockholm, Sweden, 4 The Program in Epithelial Biology, Stanford University School of Medicine, California, USA, CA and 5 Department of Medical Biochemistry and Microbiology (IMBIM), Uppsala University, Uppsala, Sweden

16.40-16.50

[ABSTRACT 324]

Skin Microbiota Activate the Aryl Hydrocarbon Receptor via Tryptophan Metabolism

AE Elias,1 AJ McBain2 and CA O’Neill1 1 Division of Musculoskeletal and Dermatological Sciences, University of Manchester, Manchester, United Kingdom and 2 Division of Pharmacy and Optometry, University of Manchester, Manchester, United Kingdom

16.50-17.00

[ABSTRACT 180]

The antimicrobial peptide derived from insulin-like growth factor-binding protein 5 promotes skin barrier function and relieves dermatitis-like symptoms in a mouse model of atopic dermatitis

HL Nguyen,2,1 G Peng,2,1 J Jujillo-Paez,2 H Yue,2 K Okumura,2 H Ogawa,2 S Ikeda2 and F Niyonsaba2,3 1 Dermatology and Allergology, Juntendo Daigaku, Tokyo, Japan, 2 Atopy (Allergy) Research Center, Juntendo University, Tokyo, Japan and 3 Faculty of International Liberal Arts, Juntendo University, Tokyo, Japan

 

17.00-17.10

[ABSTRACT 546]

Epidermal growth factor receptor as a key regulator of the immune privilege

K Strobl, R Jin, L Artner, J Klufa, M Sibilia and T Bauer Center for Cancer Research, Medical University of Vienna, Vienna, Austria

 

17.10-17.20

[ABSTRACT 436]

Keratinocyte Regnase-1, a down-modulator of skin inflammation, contributes to protection from carcinogenesis through regulating COX-2

H Morisaka,1 M Takaishi,1 S Akira2,3 and S Sano1 1 Dermatology, Kochi Medical School, Kochi University, Kochi, Japan, 2 Laboratory of Host Defence, World Premier Institute Immunology Frontier Research Center, Osaka University, Suita, Japan and 3 Department of Host Defence, Research Institute for Microbial Diseases, Osaka University, Suita, Japan

 

17.20-17.30

[ABSTRACT 330]

Poly(ADP-ribose) polymerase (PARP)-2 promotes inflammation in psoriasis by regulating estradiol biosynthesis in keratinocytes

D Antal,1 A Par,3 K Hegyi,2 I Kovacs,3 A Szegedi,2 P Bai1,4,5 and M Szanto1 1 Department of Medical Chemistry, University of Debrecen, Debrecen, Hungary, 2 Department of Dermatology, University of Debrecen, Debrecen, Hungary, 3 Department of Pathology, University of Debrecen, Kenézy Gyula Campus, Debrecen, Hungary, 4 MTA-DE Lendület Laboratory of Cellular Metabolism, University of Debrecen, Debrecen, Hungary and 5 Research Center for Molecular Medicine, University of Debrecen, Debrecen, Hungary

 

 

17.30-17.40

[ABSTRACT 331]

Mitochondrial stress contributes to atopic dermatitis

DC Minzaghi,1 P Pavel,1 G Leman,1 F Gruber,2 S Oberreiter,1 S Blunder,1 R Gruber1 and S Dubrac1 1 Department of dermatology, Medical University of Innsbruck, Austria, Innsbruck, Austria and 2 Dermatology, Medical University Vienna, Vienna, Austria

 

17.40-17.50

[ABSTRACT 319]

S. aureus can induce NLRP1 inflammasome activation in patients with atopic dermatitis

H Vaher,1 K Kingo,1 P Kolberg,1 K Alasoo,1 L Raam,2 T Tenson,1 U Mrowietz,3 S Weidinger,3 K Kingo2 and A Rebane1 1 University of Tartu, Tartu, Estonia, 2 Tartu University Hospital, Tartu, Estonia and 3 Christian-Albrechts-University of Kiel, Kiel, Germany