Concurrent 7: Melanoma and Other Skin Cancers

Date: Saturday 1 October 2022
Time: 12.30-14.00

Room 1

Chairs: Khiarash Khosrotehrani (Brisbane), Remco Van Doorn (Leiden)

Concurrent talks are 8 minutes plus 2 minutes discussion







GRPR is an effective target for melanoma

J Raymond, M Pouteaux, V Petit, Z Aktary, L Larue and V Delmas Team Larue – INSERM U1021 – CNRS UMR3347, Institut Curie, Orsay, France




A non-transcriptional role of the oncoprotein YAP in cutaneous squamous cell carcinoma

J Bojko and G Walko Department of Life Sciences, University of Bath, Bath, United Kingdom




PVT1 is overexpressed in cutaneous squamous cell carcinoma and acts as an oncogenic long non-coding RNA

C Li,2 C Sun,2 K Das Mahapatra,1 J Lapins,3 V Kahari,4 E Sonkoly2 and A Pivarcsi2 1 Karolinska Institutet, Stockholm, Sweden, 2 Uppsala University, Uppsala, Sweden, 3 Karolinska University Hospital, Stockholm, Sweden and 4 Turku University Hospital and University of Turku, Turku, Finland




Single-cell RNA sequencing reveals specific T cell and fibroblast populations that can distinguish early mycosis fungoides from parapsoriasis and atopic dermatitis lesions

N Alkon,2 M Drach,2 L Shaw,2 U Mann,2 J Valencak,2 W Weninger,2 J Griss,2 M Farlik,2 C Jonak2 and PM Brunner1,2 1 Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY and 2 Medical University of Vienna, Vienna, Austria




The exosome-associated miR-146a modulates cellular senescence and senescence-associated secretory phenotype (SASP) in Head and Neck SCC (HNSCC)

BL Hill, A Calder, J Flemming, Y Guo, S Gilmore, A Linnenbach, A South, L Harshyne, A Luginbuhl and MG Mahoney Thomas Jefferson University, Philadelphia, PA




CD271 modulates cutaneous squamous cell carcinoma growth and invasion in patient-derived spheroids and zebrafish avatar

M Quadri,1 L Reggiani Bonetti,2 R Panini,2 N Tiso,3 M Morasso,4 R Lotti,1 A Marconi,1 C Pincelli1 and E Palazzo1 1 ChiMoMo, University of Modena and Reggio Emilia, Modena, Italy, 2 Pathology, UNIMORE, Modena, Italy, 3 Biology, UNIPD, Padova, Italy and 4 Lab. Skin Biology, NIH, Bethesda, MD




Inhibiting insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) reduces tumor development in the basal cell carcinoma mouse model PTCH+/-

C Harris,1 M Hajahmed,1 O Odubanjo,1 C Yedjou,4 V Spiegelman,3 J Chamcheu,2 T Roy,2 S Boetang,2 R Chamcheu2 and F Noubissi1 1 Biology, Jackson State University, Jackson, MS, 2 University of Louisiana at Monroe, Monroe, LA, 3 Pennsylvania State University, Hershey Medical Center, Hershey, PA, Hershey, PA and 4 Department of Biology, Florida A&M University, Tallahassee, FL




Integrated multi-omics reveals cellular and molecular interactions governing the invasive niche of basal cell carcinoma

L Yerly,1 C Pich Bavastro,1 J Di Domizio,1 T Wyss,2 S Tissot,3 M Cangkrama,4 M Gilliet,1 S Werner4 and F Kuonen1 1 Department of Dermatology and Venereology, Lausanne University Hospital Center, Lausanne, Switzerland, 2 Swiss Institute of Bioinformatics, Lausanne, Switzerland, 3 Department of Oncology, Lausanne University Hospital Center, Lausanne, Switzerland and 4 Department of Biology, Institute of Molecular Health Sciences, ETH Zurich, Zürich, Switzerland




A multi-scale spatial atlas of human skin across anatomical sites and cutaneous malignancy reveals novel cell states and repurposing of fibroblast subpopulations in skin cancer stroma

C Ganier,1 X Du-Harpur,1 GE Herrera,2 J Gabriel,1 N Harun,1 F Watt1 and M Lynch1 1 Centre for Gene Therapy and Regenerative Medicine, King’s College London, London, United Kingdom and 2 Centre for Developmental Neurobiology, King’s College London, London, United Kingdom