Date: Saturday 1 October 2022
Time: 12.30-14.00
Room 2
Chairs: Nikolas Haas (Brisbane), Eli Sprecher (Tel Aviv)
Concurrent talks are 8 minutes plus 2 minutes discussion
PROGRAM
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12.30-12.40 | [LB039] Palmoplantar keratoderma as a clinical feature of pathogenic variants in the filaggrin gene Julia Clabbers1, Marieke Bolling2, Charlotte Burms1, Maaike Vreeburg3, Henny Lemmink4, Peter van den Akker4, Peter Steijlen1, Michel van Geel1, Antoni Gostyński1 1Department of Dermatology, Maastricht University Medical Centre+, Maastricht, The Netherlands, 2Department of Dermatology, University Medical Centre Groningen, Groningen, The Netherlands, 3Department of Clinical Genetics, Maastricht University Medical Centre+, Maastricht, The Netherlands, 4Department of Genetics, University Medical Centre Groningen, Groningen, The Netherlands
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12.40-12.50 | [LB025] Neurotrophin Signaling in Epithelial to Mesenchymal Transition as a Potential Target in Melanoma Therapy Laura Bertoni1, Marika Quadri3, Paola Sena1, Giulia Orlandi1, Elisabetta Palazzo3, Roberta Lotti3, Francesca Farnetani2, Alessandra Marconi3 1Morphological Sciences Sections, Dept of Surgical, Medical, Dental and Morphological Sciences, UNIMORE, Modena, Italy, 2Dermatology Unit, Dept of Surgical, Medical, Dental and Morphological Sciences, University of Modena and Reggio Emilia, Modena, Italy, 3DermoLab, Dept of Surgical, Medical, Dental and Morphological Sciences, UNIMORE, Modena, Italy
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12.50-13.00 | [LB017] Uncoupling Desmosomal Cadherin Adhesion Activates Stem Cells in the Quiescent Hair Follicle William V.J. Hariton,1,2,3 Katja Schulze,3,4,5 Roman Schwob,3,4 Andrew M. Overmiller,6 My G. Mahoney,6 Luca Borradori,1,3 Beyza S. Sayar,1,2,3 Arnaud Galichet,1,3,4 Eliane J. Müller1,2,3,4 1Department of Dermatology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland, 2 Department for BioMedical Research, Molecular Dermatology and Stem Cell Research, University of Bern, Bern, Switzerland, 3DermFocus, Vetsuisse Faculty, University of Bern, Bern, Switzerland, 4 Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, Bern, Switzerland, 5Genentech Inc., Roche, San Francisco, CY, USA, 6Department of Dermatology and Cutaneous Biology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
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13.00-13.10 | [LB003] CK1⍺ Inhibition in Keratinocytes of Mc1r Defective Mice Prevents Ultraviolate-induced Skin Damage Chung-Hsing Chang1,2,3, Wei-Ping Huang2,3, Ho-Jen Chen3, Chien-Hung Chen3 1Doctoral Degree Program in Translational Medicine, Tzu Chi University and Academia Sinica, Hualien, Taiwan 2Institute of Medical Sciences, Tzu Chi University, Hualien, Taiwan 3Skin Institute, Hualien Tzu Chi Hospital, Hualien, Taiwan
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13.10-13.20 | [LB009] IL-4/IL-13 inhibitors for atopic dermatitis induce psoriatic rash transcriptionally close to pustular psoriasis Chloé Grolleau1,2, Andreea Calugareanu2,3, Sarah Demouche1,2, Audrey Nosbaum3, Delphine Staumont-Sallé4, Hélène Aubert5, Antonio Alberdi6, Alexandre How-Kit7, Jean-David Bouaziz1,2, Hélène Le-Buanec2 1Dermatology department, Hôpital Saint Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris 2Université de Paris, INSERM U976 – HIPI Unit, Institut de Recherche Saint-Louis, Paris, France 3Dermatology department, CHU Lyon Centre, Hospices civils de Lyon (HCL), France 4Dermatology department, CHU Lille, U1286 Inserm INFINITE, Univ. Lille, Lille, France 5Dermatology department, Nantes University Hospital, Nantes, France 6Plateforme Technologique IRSL, UFR Médecine, Université de Paris, Hôpital Saint-Louis, Paris, France. 7Laboratory of Genomics, Foundation Jean Dausset-CEPH, Paris, France
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13.20-13.30 | [LB032] Driver gene combinations dictate cutaneous squamous cell carcinoma disease continuum progression Peter Bailey1, Rachel Ridgway2, Christina Schoenherr2, Mairi Treanor-Taylor2, Alexander J. Stratigos3, Charlotte M. Proby4, Catherine A. Harwood5, Owen J. Sansom2, Irene M. Leigh5 and Gareth J. Inman2 1Institute of Cancer Sciences, University of Glasgow, United Kingdom 2Cancer Research UK Beatson Institute, Glasgow, United Kingdom 31st Department of Dermatology – Venereology, Andreas Sygros Hospital, National and Kapodistrian University of Athens, School of Medicine, Greece 4Jacqui Wood Cancer Centre, University of Dundee, United Kingdom 5Centre for Cell Biology and Cutaneous Research, Blizzard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, United Kingdom
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13.30-13.40 | [LB042] Targeting Melanoma Plasticity to Improve both Targeted and Immune Therapy Satoru Sugihara1, Jacinta Simmons2, Yimeng Guan1, Gency Gunasingh1, Jordan Kumar1, Rituparna Bhatt1, Riccardo Dolcetti1, Glen Boyle2, Loredana Spoerri1, Nikolas K. Haass1 1The University of Queensland Diamantina Institute, The University of Queensland, Brisbane, QLD, Australia 2QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia
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13.40-13.50 | [LB033] Clinical trial using dermal open flow microperfusion (dOFM) elucidates mechanisms of dupilumab (Dupixent) on downstream signal pathways and indicates differences in local and systemic effects Barbara Ehall1, Anita Eberl2, Manfred Bodenlenz2, Katrin Tiffner2, Thomas Birngruber2, Eva Svehlikova1, Thomas Pieber1 1Division for Endocrinology and Diabetology, Department for Internal Medicine, Medical University of Graz, Graz, Austria; 2HEALTH- Institute of Biomedicine and Health Science, Joanneum Research, Graz, Austria
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13.50-14.00 | Tyrosine-derivated-peptide increases hair follicles melanogenesis via a MITF, CREB, and TYRP1 dependent pathway Philippe Mondon, Caroline Ringenbach, Thomas Ondet, Olivier Peschard, Emmanuel Doridot, Richard Leroux SEDERMA, Le Perray-en-Yvelines, France |