PROGRAM

[ABSTRACT 547]

CDK9 Kinase Activation in Association with AFF1-SEC Initiate Epidermal Progenitor differentiation

S Lloyd and X Bao Northwestern University, Evanston, IL

[ABSTRACT 549]

Temporary cell cycle arrest in human scalp hair follicles and their epithelial stem cells by ALRN-6924: A novel strategy to selectively protect p53-wildtype cells against paclitaxel-induced alopecia

J Gherardini,¹ AD Annis,² J Chéret,¹ M Aivado² and R Paus^1 1 Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL and ² Aileron Therapeutics, Boston, MA

[ABSTRACT 550]

aPKC regulates the spindle orientation machinery to promote planar cell divisons

S Perot,¹ J Nafisi,¹ F Telkamp,¹ M Mapelli² and C Niessen^1 1 Department Cell Biology of the Skin & CECAD, CMMC, University Hospital of Cologne, University of Cologne, Köln, Germany and ² IEO, European Institute of Oncology IRCCS, Milan, Italy

[ABSTRACT 182]

ΔNp63-mediated repression of the lncRNA NEAT1 modulates epidermal differentiation

A Peschiaroli,¹ C Fierro,² V Gatti,¹ V La Banca,² A Mauriello,² M Montanaro,² M Fanciulli,³ S Scalera,³ G Melino² and G Calin^{4 1} Department of Biomedicine, Institute of Translational Pharmacology IFT-CNR, Rome, Italy, ² Department of Experimental Medicine, University of Rome “Tor Vergata”, Rome, Italy, ³ Department of Research, IRCCS Regina Elena National Cancer Institute, Rome, Italy and ⁴ Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX

[ABSTRACT 511]

Three-dimensional culture of human sensory neurons derived from iPS cells in a pigmented and endothelialized tissue-engineered reconstructed skin enriched with Schwann cells

S Heraud,¹ F Lejeune,² C Muther,² S Forestier,² A Thépot,¹ G Gendronneau² and M Dos Santos^1 1 LABSKIN CREATIONS, Lyon, France and ² CHANEL P&B, PANTIN, France

[ABSTRACT 518]

Nutrient and stress sensing as novel physiological regulator of human hair pigmentation and greying: Role of mTORC1 activity

T Suzuki,¹ J Chéret,¹ FD Scala,¹ J Gherardini,¹ J O’Sullivan,¹ G Epstein-Kuka,² AJ Bauman,³ C Demetriades4 and R Paus^{1,5,6 1} Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, ² Foundation for Hair Restoration, Miami, FL, ³ Bauman Medical Group, Boca Raton, FL, ⁴ Max Planck Institute for Biology of Ageing (MPI-AGE), Cologne, Germany, ⁵ Monasterium Laboratory, Münster, Germany and ⁶ CUTANEON, Hamburg, Germany

[ABSTRACT 512]

Varicella-zoster virus in actively spreading segmental vitiligo skin

M Cario,^1,2,3 Y Gauthier,⁴ S Lepreux,⁵ J Rambert,² A Dakdaki,⁶ M Lafon,^7,8 R Abouqal^9,10 and L Benzekri^{11,12 1} University Bordeaux Inserm U1312, Bordeaux, France, ² Aquiderm, Bordeaux, France, ³ National reference for rare skin diseases, Bordeaux, France, ⁴ Vitiligo and Melasma Research association, Bordeaux, France, ⁵ Pathology Department, Hopital Robert Boulin CHR Libourne, Libourne, France, ⁶ Tumor Bank and Tumor Biology Laboratory, CHU Bordeaux, Bordeaux, France, ⁷ Department of Virology Bordeaux University Hospital, Bordeaux, France, ⁸ Bordeaux University, CNRS UMR5234, Bordeaux, France, ⁹ Laboratory of Biostatistics, Clinical Research and Epidemiology, Mohammed V University in Rabat, Rabat, Morocco, ¹⁰ Acute Medical Unit, Ibn Sina Teaching Hospital, Rabat, Morocco, ¹¹ Mohammed V University, Rabat, Morocco and ¹² Dermatology Department, Ibn Sina Teaching Hospital, Pigmentary Disorders outpatient clinic, Rabat, Morocco

[ABSTRACT 513]

Ultraviolet radiation exposure differentially regulates skin metabolites in dependence of the microbiome

V Patra,^1,2 Y Clement,³ N Bordag,² H K.efeler,⁴ J Nicolas,⁵ M Vocanson,¹ S Ayciriex³ and P Wolf^{2,6 1} Centre International de Recherche en Infectiologie, Lyon, France, ² Department of Dermatology and Venereology, Medical University of Graz, Graz, Austria, ³ Institute of Analytical Sciences, UMR 5280 CNRS, University Claude Bernard Lyon 1, Villeurbanne, France, ⁴ Core Facility for Mass Spectrometry, Medical University of Graz, Graz, Austria, ⁵ Allergy and Clinical Immunology Department, Lyon Sud University Hospital, Lyon, France and ⁶ BioTechMed Graz, Graz, Austria