Concurrent 9: Photobiology and Pigmentation

Date: Saturday 1 October 2022
Time: 12.30-14.00

Room 3

Chairs: Matthew Caley (London), Muriel Cario-André (Bordeaux)

Concurrent talks are 8 minutes plus 2 minutes discussion







CDK9 Kinase Activation in Association with AFF1-SEC Initiate Epidermal Progenitor differentiation

S Lloyd and X Bao Northwestern University, Evanston, IL




Temporary cell cycle arrest in human scalp hair follicles and their epithelial stem cells by ALRN-6924: A novel strategy to selectively protect p53-wildtype cells against paclitaxel-induced alopecia

J Gherardini,1 AD Annis,2 J Chéret,1 M Aivado2 and R Paus1 1 Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL and 2 Aileron Therapeutics, Boston, MA




aPKC regulates the spindle orientation machinery to promote planar cell divisons

S Perot,1 J Nafisi,1 F Telkamp,1 M Mapelli2 and C Niessen1 1 Department Cell Biology of the Skin & CECAD, CMMC, University Hospital of Cologne, University of Cologne, Köln, Germany and 2 IEO, European Institute of Oncology IRCCS, Milan, Italy




ΔNp63-mediated repression of the lncRNA NEAT1 modulates epidermal differentiation

A Peschiaroli,1 C Fierro,2 V Gatti,1 V La Banca,2 A Mauriello,2 M Montanaro,2 M Fanciulli,3 S Scalera,3 G Melino2 and G Calin4 1 Department of Biomedicine, Institute of Translational Pharmacology IFT-CNR, Rome, Italy, 2 Department of Experimental Medicine, University of Rome “Tor Vergata”, Rome, Italy, 3 Department of Research, IRCCS Regina Elena National Cancer Institute, Rome, Italy and 4 Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX




Three-dimensional culture of human sensory neurons derived from iPS cells in a pigmented and endothelialized tissue-engineered reconstructed skin enriched with Schwann cells

S Heraud,1 F Lejeune,2 C Muther,2 S Forestier,2 A Thépot,1 G Gendronneau2 and M Dos Santos1 1 LABSKIN CREATIONS, Lyon, France and 2 CHANEL P&B, PANTIN, France




Nutrient and stress sensing as novel physiological regulator of human hair pigmentation and greying: Role of mTORC1 activity

T Suzuki,1 J Chéret,1 FD Scala,1 J Gherardini,1 J O’Sullivan,1 G Epstein-Kuka,2 AJ Bauman,3 C Demetriades4 and R Paus1,5,6 1 Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, 2 Foundation for Hair Restoration, Miami, FL, 3 Bauman Medical Group, Boca Raton, FL, 4 Max Planck Institute for Biology of Ageing (MPI-AGE), Cologne, Germany, 5 Monasterium Laboratory, Münster, Germany and 6 CUTANEON, Hamburg, Germany





Varicella-zoster virus in actively spreading segmental vitiligo skin

M Cario,1,2,3 Y Gauthier,4 S Lepreux,5 J Rambert,2 A Dakdaki,6 M Lafon,7,8 R Abouqal9,10 and L Benzekri11,12 1 University Bordeaux Inserm U1312, Bordeaux, France, 2 Aquiderm, Bordeaux, France, 3 National reference for rare skin diseases, Bordeaux, France, 4 Vitiligo and Melasma Research association, Bordeaux, France, 5 Pathology Department, Hopital Robert Boulin CHR Libourne, Libourne, France, 6 Tumor Bank and Tumor Biology Laboratory, CHU Bordeaux, Bordeaux, France, 7 Department of Virology Bordeaux University Hospital, Bordeaux, France, 8 Bordeaux University, CNRS UMR5234, Bordeaux, France, 9 Laboratory of Biostatistics, Clinical Research and Epidemiology, Mohammed V University in Rabat, Rabat, Morocco, 10 Acute Medical Unit, Ibn Sina Teaching Hospital, Rabat, Morocco, 11 Mohammed V University, Rabat, Morocco and 12 Dermatology Department, Ibn Sina Teaching Hospital, Pigmentary Disorders outpatient clinic, Rabat, Morocco





Ultraviolet radiation exposure differentially regulates skin metabolites in dependence of the microbiome

V Patra,1,2 Y Clement,3 N Bordag,2 H K.efeler,4 J Nicolas,5 M Vocanson,1 S Ayciriex3 and P Wolf2,6 1 Centre International de Recherche en Infectiologie, Lyon, France, 2 Department of Dermatology and Venereology, Medical University of Graz, Graz, Austria, 3 Institute of Analytical Sciences, UMR 5280 CNRS, University Claude Bernard Lyon 1, Villeurbanne, France, 4 Core Facility for Mass Spectrometry, Medical University of Graz, Graz, Austria, 5 Allergy and Clinical Immunology Department, Lyon Sud University Hospital, Lyon, France and 6 BioTechMed Graz, Graz, Austria