Plenary 2

Date: Friday 30 September 2022
Time: 09.30-11.00


Chairs: Leopold Eckhart, Rachel Watson


Plenary talks are 9 minutes plus 3 minutes discussion







PPAR-γ promotes cystine uptake to prevent unchecked lipid ROS and cell death in Th9 cells

C Bazzini, NL Bertschi, F Luther, O Steck, N Begré and C Schlapbach Dermatology, Inselspital, Bern University Hospital, Bern, Switzerland




Interleukin (IL)-26 drives pathogenic IL-17A responses through a TH17-keratinocyte crosstalk

A Fries,1 F Saidoune,1 F Kuonen,1 C Conrad,1 I Dupanloup,2 A Guerra de Souza,2 N Fournier,2 R Gottardo,3 J Di Domizio1 and M Gilliet1 1 Dermatology, University Hospital Lausanne CHUV, Lausanne, Switzerland, 2 Translational Data Science, Swiss Institute of Bioinformatics, Lausanne, Switzerland and 3 Biomedical Data Sciences Center, CHUV, UNIL, and Swiss Institute of Bioinformatics, Lausanne, Switzerland




KLF4 variants: a novel cause of palmoplantar keratoderma

K Malovitski,1,2 O Sarig,1 S Assaf,1,2 J Mohamad,1,2 S Bergson,1,2 A Peled,1,2 M Eskin-Schwartz,3,4 A Gat,5 M Pavlovsky1,2 and E Sprecher1,2 1 Division of Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, 2 Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, 3 Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel, 4 Genetic Institute, Soroka University Medical Center, Beer Sheva, Israel and 5 Insititute of Pathology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel




STAT3/5 locus gain is a disease marker and therapeutic target in leukemic/cutaneous T cell lymphoma

S Dey,1,3 H Sorger,2,3 P Vieyra-Garcia,1 A Teufelberger,1 M Herling,4 E Heitzer,5 PT Gunning,6 L Kenner,3 R Moriggl2 and P Wolf1 1 Department of Dermatology, Medical University of Graz, Graz, Austria, 2 University of Veterinary Medicine, Vienna, Austria, 3 Medical University of Vienna, Vienna, Austria, 4 Department of Medicine I, CECAD and CMMC, Cologne University, Cologne, Germany, 5 Institute of Human Genetics, Medical University of Graz, Graz, Austria and 6 University of Toronto Mississauga, Mississauga, ON, Canada




Perivascular niches dictate developmental cellular hierarchies during melanoma growth

P Karras,1 I Bordeu,2 J Pozniak,1 A Nowosad,1 C Pazzi,1 N Van Raemdonck,1 E Landeloos,1 C Blanpain,3 F Rambow1 and J Marine1 1 VIB Center for Cancer Biology, Leuven, Belgium, 2 Department of Applied Mathematics and Theoretical Physics, Centre for Mathematical Sciences, University of Cambridge, Cambridge, United Kingdom and 3 Free University of Brussels, Brussels, Belgium




Schwann cells – an unexpected key player in keloid formation

M Direder,1,2 T Weiss,3 D Copic,1,2 V Vorstandlechner,3 K Klas,1,2 M Laggner,1,2 M Wielscher,4 D Bormann,1,2 HJ Ankersmit1,2 and M Mildner4 1 Thoracic Surgery, Medical University of Vienna, Vienna, Austria, 2 Aposcience AG, Vienna, Austria, 3 Plastic, Reconstructive and Aesthetic Surgery, Medical University of Vienna, Vienna, Austria and 4 Dermatology, Medical University of Vienna, Vienna, Austria




Risk of severe COVID-19 outcomes associated with immune-mediated inflammatory diseases and immune modifying therapies: a nationwide cohort study in the OpenSAFELY platform

S Langan,1 C Smith2 and T Collaborative3 1 London School of Hygiene and Tropical Medicine, London, United Kingdom, 2 King’s College, London, United Kingdom and 3 University of Oxford, Oxford, United Kingdom