Abdoel is the head of the Dermatology Laboratory at LUMC, specializing in 3D skin modeling in translational dermatological research. In the scope of developing and optimizing advanced in vitro skin models, their work focus on fibroblast plasticity and drug efficacy in dynamic crosstalk between tumor and the tumor microenvironment (TME) in cancers including melanoma and Cutaneous T-cell Lymphoma. Beyond Dermato-oncology, their research extends to modeling diverse skin conditions (e.g., atopic dermatitis, psoriasis, wound healing, skin aging and skin microbiome) to better understand skin pathophysiology, in collaboration with both academic and industrial partners.

With a background in tissue engineering and cell biology, Abdoel has been dedicated to leverage these skin models for both fundamental research and industrial collaborations, aiming to advance therapeutic development and innovative testing strategies in the fields of skin health and skin cancer. Their recent research highlights include the identification of small-molecule inhibitors for cancer-associated fibroblast reprogramming, exploration nanoparticle-based drug delivery systems, and investigation of therapeutics-induced TME remodeling.

At the ESDR 2025 in Antwerp, Abdoel will present insights on targeting tumor-stroma interactions in 3D models, emphasizing the pivotal role of CAFs in shaping therapeutic outcomes and advancing scientific innovation in cancer treatment.

For collaborations, contract research opportunities, or discussions, feel free to connect via a.ghalbzouri@lumc.nl or via LinkedIn