I am a dermatology registrar and an honorary clinical research fellow in Professor John McGrath’s Genetic Skin Disease Group at St John’s Institute of Dermatology. My research focus is on novel therapeutics: gene and cell therapies in particular, for epidermolysis bullosa (EB), an inherited blistering skin disease. I graduated from Guy’s, King’s and St Thomas’ School of Medicine in 2008 with MBBS and BSc (Hons) in Neuroscience and Basic Medical Sciences. I completed 5 years of training in general internal medicine in the London Deanery and obtained the MRCP (UK) in 2012. In 2013, I joined St John’s Institute of Dermatology as a clinical fellow, and subsequently in 2014 as a clinical research fellow in Professor John McGrath’s Genetic Skin Disease Group when I embarked on a PhD in Genetics and Molecular Medicine on the topic of “Development and clinical application of gene therapy in recessive dystrophic epidermolysis bullosa (RDEB)”. As part of my PhD project, I led and completed a first-in-man phase I clinical trial of autologous fibroblast gene therapy for adults with RDEB. To date, I have had >4.5 years of experience in the translational journey of gene and cell therapies for genetic skin diseases, working with both national and international collaborators. My current aim is to develop spray-on gene therapy for RDEB whilst testing human applications of the gene, cell and other novel therapies for EB.
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