Sanofi Regeneron Symposium
Date: Friday 30 September 2022
Time: 13:15–14:30 CET
Duration: 75 min
Title: Inside Atopic Dermatitis: Type 2 Inflammation Underlies Skin Barrier and Neuroimmune Dysfunction
Objectives:
– Educate on the latest understanding of the interrelated mechanisms that drive AD:1) Type 2 inflammation, both systemic and local
2) Dysfunction of the skin barrier, including dysbiosis
3) Neuroimmune dysregulation
– Share evidence demonstrating that type 2 inflammation is a key driver of dysfunction of both the skin barrier, including dysbiosis, and neuroimmune dysregulation – and driver of normalization of the same mechanisms
– Discuss the latest findings from clinical studies on how targeting type 2 inflammation can restore and normalize skin barrier function, including dysbiosis, and ex vivo studies demonstrating the role of type 2 inflammation in neuroimmune dysregulation
Speakers:
- Chair: Laurent Misery (France)
- Speakers: Lisa A. Beck (USA) and Simon Danby (UK)
PROGRAM
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13.15–13.18 | Welcome and Introduction Laurent Misery (France)
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13.18–13-38 | Skin Barrier Dysregulation has Multifaceted Interactions with Type 2 Inflammation Lisa A. Beck (USA)
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13.38–13.53 | The Neuroimmune Axis and Neuroinflammatory Mechanism of Pruritus Laurent Misery (France)
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13.53–14.13 | Clinical Evidence of Barrier Normalization by Targeting Type 2 Inflammation Simon Danby (UK)
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14.13–14.28 | Panel Discussion All faculty
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14.28–14.30 | Summary and Closing Remarks Laurent Misery (France) |