European Epidermal Barrier Research Network

Amphitheatre B

17th Meeting of the European Epidermal Barrier Research Network (E2BRN)

Date: Wednesday 18 September 2019, 08.25-18.30
Room: Amphitheatre B

Scientific Organising Committee: Hanna Niehues (Nijmigen,The Netherlands), Dusko Ilic (London, United Kingdom)

All delegates are required to register for the ESDR meeting.


08.25-08.30 Opening remarks
Johanna Brandner (Germany)

Session 1 chaired by Johanna Brandner & Ana Costa


08.30-09.00 Epidermal lipids in inflammatory skin diseases
Joke Bouwstra (The Netherlands)
09.00-09.30 AFM-measured corneocyte rigidity in health and atopic dermatitis
Marek Haftek (France)
09.30-10.00 Plasmin and the barrier
Rainer Voegeli (Switzerland)
10.00-10.30 Short talks selected from abstracts

Variability of topical penetration data from dermal open flow microperfusion might be attributed to variability in skin barrier function and follicular penetration
Manfred Bodenlenz (Austria)

Quantitative measurement of in vivo skin penetration of topically applied materials by Raman spectroscopy
Peter Caspers (The Netherlands)


10.30-11.00 Coffee Break


Session 2 chaired by Hanna Niehues & Julia Lachner


11.00-11.30 Applications of 3D skin equivalents to study skin disease pathophysiology and therapeutics
Ellen van den Bogaard (The Netherlands)
11.30-12.00 RIPK4, an important mediator maintaining epidermal homeostasis
Wim Declerq (Belgium)
12.00-12.30 Short talks selected from abstracts

Infection by dermatophytes of reconstructed human epidermis is impaired by PD169316 via inhibition of fungal growth
Émilie Faway (Belgium)

TARgetting the cutaneous microbiota in atopic dermatitis by coal tar via AHR-dependent induction of antimicrobial peptides
Jos Smits (The Netherlands)


12.30-13.30 Lunch


13.30-14.30 Poster Viewing


  Session 3 chaired by Dusko Ilic & Irini Dijkhoff


14.30-15.00 Making sense of GWAS: genetic mechanisms in skin barrier formation
Sara Brown (UK)
15.00-15.30 Autophagy at the epidermal barrier
Leopold Eckhart (Austria)
15.30-16.00 Newly identified components of a stratum corneum structure known for a long time, the cornified cell envelope
Michel Simon (France)
16.00-16.30 Short talks selected from abstracts

The novel whey acidic protein WFDC12 is expressed in particular terminally differentiated keratinocytes
Polina Kalinina (Austria)

Osmolyte-mediated cell volume regulation is dysregulated by ageing and following UV exposure in human skin
April Foster (US)


16.30-17.00 Coffee Break


  Session 4 chaired by Patrick Zeeuwen & Joshua Broussard


17.00-17.30 Cell adhesion and polarity signalling in making and maintaining the epidermal barrier
Matthias Rübsam (Germany)

17.30-18.00 Protective effect of Aquaphilus dolomiae Extract on Tight Junction-barrier function in a Staphylococcus aureus-infected-AD model
Helène Duplan (France)
18.00-18.15 Poster Prizes


18.15-18.30 E2BRN network meeting


19.30 Dinner